Pancreatic Mixed Neuroendocrine Non Neuroendocrine Neoplasm, a rare malignancy, co-existing with Prostatic Carcinoma: A Case Report.

Abstract

Mixed neuroendocrine non neuroendocrine neoplasms present a diagnostic challenge. They are heterogenous malignancies that occur primarily in the GI tract and are characterized as having at least 30% each of exocrine and e ndocrine component occurring at the same site. Mixed  neuroendocrine non neuroendocrine neoplasms are difficult to recognize due to their specific diagnostic criteria; occur rarely, and are infrequently described i n literature. On ly 30 cases of this tumor occurring in the pancreas have been previously reported. Men with prostatic carcinoma have occasionally been found to develop a secondary primary tumor. However, Pancreatic mixed neuroendocrine non neuroendocrine neoplasm has not been previously reported in conjunction with prostate cancer. Herein, we report a case of an elderly male with preexisting advanced prostatic malignancy, found to have a pancreatic mixed neuroendocrine non neuroendocrine neoplasm, on an endoscopic biopsy sample.