Harnessing CRISPR Technology for Precision Gene Editing: Innovations and Ethical Considerations
Mots-clés :
CRISPR-Cas9, genome editing, genetic engineering, precision medicine, bioethics, off-target effects, human enhancement, equitable accessRésumé
CRISPR-Cas9 technology has revolutionized the field of genetic engineering, offering unprecedented precision and efficiency in altering genomes. This review delves into the latest advancements in CRISPR technology, exploring its diverse applications in fields such as medicine, agriculture, and biotechnology. We discuss the technical innovations that have enhanced the specificity and efficacy of CRISPR-Cas9, including the development of novel guide RNA designs and optimized Cas9 variants. Furthermore, we examine the ethical implications of this powerful technology, addressing concerns related to unintended off-target effects, potential misuse for human enhancement, and equitable access to CRISPR-based therapies. By critically analyzing the scientific and ethical dimensions of CRISPR technology, this review aims to provide a comprehensive understanding of its transformative potential and the responsible stewardship required for its safe and beneficial application.
